X-ray crystal structure of MENT: evidence for functional loop–sheet polymers in chromatin condensation
نویسندگان
چکیده
منابع مشابه
X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Most serpins are associated with protease inhibition, and their ability to form loop-sheet polymers is linked to conformational disease and the human serpinopathies. Here we describe the structural and functional dissection of how a unique serpin, the non-histone architectural protein, MENT (Myeloid and Erythroid Nuclear Termination stage-specific protein), participates in DNA and chromatin con...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2006
ISSN: 0261-4189,1460-2075
DOI: 10.1038/sj.emboj.7601201